About the semaglutide api price, i would like to share some info.
A post by Girish S Sonar
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As we inch closer to the generic entry window of 𝗢𝗿𝗮𝗹 𝗦𝗲𝗺𝗮𝗴𝗹𝘂𝘁𝗶𝗱𝗲, the economics remain a tough nut to crack for many generic players.
According to QYOBO https://lnkd.in/dydt9kJG, Semaglutide API prices have declined 𝟲𝟬–𝟳𝟲% since 2020, reaching a corridor of $𝟯𝟯𝟬–𝟰𝟯𝟬/𝗴 by early 2025. But even at $𝟯𝟴𝟬/𝗴, 𝗮 𝟭𝟰 𝗺𝗴 𝘁𝗮𝗯𝗹𝗲𝘁 would still require an API worth $5.32/tablet — far beyond the range of commercial feasibility in GCC.
Let’s analyze the viability using 𝗚𝗖𝗖 𝗺𝗮𝗿𝗸𝗲𝘁 𝗱𝗮𝘁𝗮 (source: Pi Pharma Intelligence https://lnkd.in/d5pqHTZD):

𝗣𝘂𝗯𝗹𝗶𝗰 𝗽𝗿𝗶𝗰𝗲𝘀 𝗳𝗼𝗿 𝗥𝘆𝗯𝗲𝗹𝘀𝘂𝘀 𝟭𝟰 𝗺𝗴 (𝟯𝟬’𝘀 𝗽𝗮𝗰𝗸):
· KSA: $4.06/tab
· UAE: $5.82/tab
· Qatar: $6.52/tab
· Kuwait: $4.61/tab
· Bahrain: $4.19/tab
· Oman: $4.87/tab
· Jordan: $4.96/tab

𝗔𝘀 𝗽𝗲𝗿 𝗦𝗙𝗗𝗔 𝗽𝗿𝗶𝗰𝗶𝗻𝗴 𝗿𝘂𝗹𝗲𝘀, the first generic in 𝗦𝗮𝘂𝗱𝗶 𝗔𝗿𝗮𝗯𝗶𝗮 would likely be listed at ~$𝟮.𝟴𝟰/𝘁𝗮𝗯 (70% of innovator price).

𝗘𝘀𝘁𝗶𝗺𝗮𝘁𝗲𝗱 𝗖𝗢𝗚𝗦 (𝗶𝗻𝗰𝗹𝘂𝗱𝗶𝗻𝗴 𝗳𝗼𝗿𝗺𝘂𝗹𝗮𝘁𝗶𝗼𝗻, 𝗰𝗼𝗻𝘃𝗲𝗿𝘀𝗶𝗼𝗻 & 𝗮𝗻𝗮𝗹𝘆𝘁𝗶𝗰𝗮𝗹):
~$𝟬.𝟲𝟬/𝘁𝗮𝗯, of which $𝟬.𝟰𝟴 would be the contribution from API.

Therefore, to make the economics work:
The Semaglutide (non-sterile) 𝗔𝗣𝗜 𝘀𝗵𝗼𝘂𝗹𝗱 𝗰𝗼𝘀𝘁 < $𝟯𝟰/𝗴 (𝗶.𝗲., < $𝟯𝟰,𝟮𝟴𝟲/𝗸𝗴).

𝗞𝗲𝘆 𝗜𝗻𝘀𝗶𝗴𝗵𝘁 𝗳𝗼𝗿 𝗚𝗲𝗻𝗲𝗿𝗶𝗰 𝗦𝘁𝗿𝗮𝘁𝗲𝗴𝘆 𝗧𝗲𝗮𝗺𝘀 𝘁𝗮𝗿𝗴𝗲𝘁𝗶𝗻𝗴 𝗚𝗖𝗖:
A viable oral semaglutide business case 𝗱𝗲𝗺𝗮𝗻𝗱𝘀 𝗔𝗣𝗜 𝗽𝗿𝗶𝗰𝗲𝘀 𝘁𝗼 𝗳𝗮𝗹𝗹 𝗯𝗲𝗹𝗼𝘄 $𝟯𝟰/𝗴 — a steep drop from current levels.

Until then, 𝗰𝗼𝗹𝗹𝗮𝗯𝗼𝗿𝗮𝘁𝗶𝗼𝗻, 𝗖𝗗𝗢 𝗶𝗻𝗻𝗼𝘃𝗮𝘁𝗶𝗼𝗻, and 𝗲𝗮𝗿𝗹𝘆 𝗹𝗶𝗰𝗲𝗻𝘀𝗶𝗻𝗴 could bridge the technical and economic challenges.

In the real market, today is 2025/09/09, the recombinant api price is around $90/g. If DMF and WC required, the price is around $130/g.

A manufacturer quoted as below:
​India/Emerging Markets:​​ 95−105/gm min. Not recommended.
​US/EU:​​ Higher (patent premium).
​Canada:​​ Expected 120−140/gm.

Anyone need semaglutide, plz contact me.
Email address: haoran.tse@gmail.com
Tel: +86 18575536586